Scope: Both general and technical articles on current technologies and methods used in biomedical and clinical engineering; societal implications of medical technologies; current news items; book reviews; patent descriptions; and correspondence. Special interest departments, students, law, clinical engineering, ethics, new products, society news, historical features and government.

From the Editor
change is in the wind
Michael Neuman
I’m writing this, my first column as
the new editor-in-chief, during the
final week of the U.S. presidential
election campaign. The U.S. citizens
are being bombarded by messages from
both major candidates talking about
change. No matter what they will do,
they will change things in Washington.
We have all heard that before, but in
politics, it seems to be a common topic.
When applying for a new job, it is
always easy to talk about what one
would do to make changes from one’s
predecessor’s activities. The same holds
true for the new editor-in-chief. Of
course, I’m looking forward to making
some changes in IEEE Engineering in
Medicine and Biology Magazine, but
unlike the presidential candidates, I
want to do this to place my own mark on
this publication rather than to even suggest
that my predecessor had not done
an excellent job. All of us associated
with the magazine owe a great debt of
gratitude to John Enderle, who has
expertly guided this magazine to its
position of prominence. This was no
small task, and I’m proud to report that I
will be taking over a quality operation.
Although John is no longer editor-inchief,
his influence will be evident in
this year’s volume. The special sections
that each issue will have have been
organized by John, and he will continue
to oversee them. Thanks, John, for a job
well done.
So what will be different you might
well ask? Not much for a while, as I
need to learn the ropes and more about
the role of this, the biomedical engineering
publication with the largest worldwide
circulation. I want this magazine
to meet the needs of you, our readers,
the IEEE Engineering in Medicine and
Biology Society (EMBS), and biomedical
engineering in general. I hope that
we will present more news of our field
as well as articles reviewing what’s new
and what’s happening in biomedical
engineering today. No, these reviews
will not be archival scientific review
papers; these belong to our sister transactions.
Instead, we will be encouraging
and commissioning authors to write
overviews of various areas, institutions,
individuals, and programs in biomedical
engineering. A model that I would like to
follow is that of the award-winning IEEE
magazine, IEEE Spectrum. However, I
can’t do this on my own; I will need your
help. Your thoughts on what you would
like to learn more about in biomedical
engineering and your volunteering to
write these articles will be important to
the success of this magazine.
I would also like to see more opinion
on these pages. I will use this column to
express some of mine, and I hope that
some of you will feel inclined to do the
same. We will welcome guest editorials
as well as letters that agree or disagree
with some of the opinions we publish.
The idea is to be a forum for discussion
of important issues in biomedical engineering.
Because the printed word
involves many delays even in our technically
advanced society, we will be
upgrading the IEEE Engineering in
Medicine and Biology Magazine Web
pages in the coming months, and there
will be opportunities for comments to
be made in a more timely fashion. I plan
to review these comments and to periodically
include some in the printed
magazine as well.
Another change that has been made
is to establish a new position of deputy
editor-in-chief. I’m pleased to welcome
Dr. Sylvestro Micera to this position.
He will help make plans and prepare
each issue as well as oversee the redevelopment
of our Web site. Sylvestro is
an assistant professor at the Scuola
Superiore Sant’Anna in Pisa, Italy, and
has been active in EMBS activities for
several years. I welcome him to the editorial
team and look forward to working
with him.
So change is in the air. Hopefully, the
changes will be for the better, and as
always, your comments and suggestions
for improvements in this publication
will be most welcome and are
encouraged.
Michael Neuman

Themes
10 Engineering Strategies for Drug Delivery
Yong Wang
12 Dendrimers in Medical Nanotechnology
Tristan Barrett, Gregory Ravizzini, Peter L. Choyke,
and Hisataka Kobayashi
23 High-Voltage, Electric Field-DrivenMicro/Nanofabrication
for Polymeric Drug Delivery Systems
Yubing Xie and James Castracane
31 BioMEMS Devices for Drug Delivery
Eric E. Nuxoll and Ronald A. Siegel
40 The Arrival of Genetic Engineering
Eugene R. Arulmuthu, David J. Williams, and Hendrik K. Versteeg
55 Transdermal Drug Delivery by Localized Intervention
T.R. Gowrishankar, Terry O. Herndon, and James C. Weaver
64 Ultrasound-Mediated Drug Delivery
Eric C. Pua and Pei Zhong
Features
76 Remote-Sensing Infrared Thermography
Eddie Y.-K. Ng and Rajendra U. Achary

Departments
3 From the Editor
Change Is in the Wind
5 President’s Message
We Can Make It Better!
7 Student’s Corner
In Retrospective: Student Events at EMBC’08
84 Emerging Technologies
Best of Both Worlds
86 Patents
The Case of the Stolen Mouse Trap
87 Senior Design
Design Verification in Capstone Design Courses
89 Engineering in Genomics
Controlling Cell Behavior Using Their High-Resolution
Light-Sensing Capability
92 Point of View
The Ice Is Broken
94 Book Reviews
96 2008 Annual Index
111 Conference Calendar

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