Clinical Management of Chronic Obstructive Pulmonary Disease, Second Edition (Lung Biology in Health and Disease)


Description:
Since the publication of the first edition chronic obstructive pulmonary disease ( COPD ), as a public health issue, has continually increased in line with the predictions of the World Health Organization - unfortunately, this trend is increasing, and by the year 2020 COPD will become one of the main killers of human life. With several important large scaled trials becoming available and our knowledge of COPD's determinants rapidly growing, it was essential to update Clinical Management of Chronic Obstructive Pulmonary Disease with a second edition that will enable physicians to stay informed, aid in the clinical diagnosis, and the proper treatment of COPD. This is the second edition of a book, significantly revised from its first edition published in 2002, which broadly addresses all aspects of chronic obstructive pulmonary disease (COPD). Both editions were inspired by the Global Initiative for Obstructive Lung Disease (GOLD) guidelines published in 2001. The book is an attempt to adopt the observations of authorities from diverse experience, providing a comprehensive review of the current state of the art respecting COPD. The audience is large and varied, but would include primary care internists, pulmonologists, and intensivists. Nurses, respiratory therapists, and rehabilitators would undoubtedly find the reference informative. It would also provide a real-life reference for basic science researchers in putting a face on applications carried out in the laboratory. There are nearly 50 contributors of international renown, although primarily from the United States, Canada, and Western Europe. This is one of the most comprehensive and up-to-date treatises that I have surveyed covering basic molecular biology and genetics underlying the disease for the clinician, epidemiology, early diagnosis, clinical presentation, and management from mildly afflicted to those requiring assisted ventilation and end-of-life palliation. The book focuses exceptionally upon the speculated growing role for pharmacotherapeutics, originally relegated to symptom palliation; that is, it makes inferences upon disease modification and impact upon mortality. In the latter respect, it offers evidence-based medicinal reviews and practice guidelines, constituents often lacking in similar undertakings. Particular emphasis is placed on objective measures of monitoring disease progress, an exercise becoming more important as survival potentially increases and upon hearing about management that might be rendered from multidisciplinary perspectives; experiences, in reality, not always afforded patients and/or their caregivers firsthand. This edition augments substantially the presentation of the last edition. Illustrations and graphics are limited, but sufficient to carry out the ends of each chapter. The bibliographies at each chapter end are extensive and relevant.

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